Bcl10 Antibody

B-cell lymphoma/leukemia 10 (Bcl10) promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK. Bcl10 may be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Bcl10 Is a substrate for MALT1 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ O95999].
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