Bcl-xL is part of the BCL-2 family of proteins that regulates apoptosis and cell cycle control. Bcl-xL is the protein product of the larger alternatively spliced isoform of Bcl-x. Bcl-xL functions similarly to BCL2 in promoting cell survival and inhibiting proliferation by promoting G0 arrest. Bcl-xL is located in the outer mitochondrial membrane and promotes cell survival by preventing mitochondrial release of cytochrome c and caspase activation in response to apoptotic signals.
Alternative names for
Bcl-xL Antibody include BCL2L1 antibody,
BCL2-like 1 antibody,
Bcl-2-like protein 1 antibody,
Apoptosis regulator Bcl-X antibody,
bcl-2-like protein 1 antibody,
apoptosis regulator Bcl-X antibody,
protein phosphatase 1, regulatory subunit 52 antibody.