BRAF Antibody

B-Raf proto-oncogene serine/threonine-protein kinase (BRAF) is a member of the raf/mil family of serine/threonine kinases. BRAF is involved in transducing mitogenic signals via the MAP kinase/ERKs signaling pathway. Mutations in BRAF are involved in a wide range of cancers such as lung, non-Hodgkin lymphoma, and colorectal cancer. Defects in BRAF are also the cause of cardiofaciocutaneous syndrome (CFC), an autosomal dominant syndrome characterized by facial anomalies, heart defects, and ectodermal abnormalities.

Alternative names for BRAF Antibody include murine sarcoma viral (v-raf) oncogene homolog B1 antibody, 94 kDa B-raf protein antibody, RAFB1 antibody, B-RAF1 antibody.