SMAR1/BANP was identified as a protein that binds the scaffold/matrix associated region of the T-cell receptor beta locus (SMAR1) and as a protein that interacts with BTG3, a member of structurally related proteins that regulate cell proliferation (BANP- BTG-associated nuclear protein). SMAR1/BANP is a DNA binding protein that is reported to be a tumor suppressor and transcriptional repressor. SMAR1/BANP can down-regulate cyclin D1 transcription by binding to the cyclin D1 promoter and through its interaction with HDAC1 (histone deacetylase 1). SMAR1 has also been shown to interact with p53 and modulate its activity.
Alternative names for
BANP/SMAR1 Antibody include Protein BANP antibody,
protein BANP antibody,
BEN domain-containing protein 1 antibody,
Btg3-associated nuclear protein antibody,
Scaffold/matrix-associated region-1-binding protein antibody,
BTG3 associated nuclear protein antibody,
scaffold/matrix-associated region-1-binding protein antibody.