The SMARCs (SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin), and BAFs (BRG1-associated factors), have been identified as components of the mammalian SWI/SNF-like chromatin-remodeling protein complexes. These multi-protein complexes are proposed to function as ATP-driven motors that translocate along DNA and destabilize nucleosomal structures to facilitate transcription factor binding. SMARCD2/BAF60B was isolated from a cDNA library in a search for proteins similar to mouse BAF60A which was identified as the paralog of the S. cerevisiae SWI/SNF component, SWP73.
Alternative names for
BAF60b/SMARCD2 Antibody include BAF60B antibody,
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 antibody,
60 kDa BRG-1/Brm-associated factor subunit B antibody,
BRG1-associated factor 60B antibody,
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 antibody,
Swp73-like protein antibody,
SWI/SNF complex 60 kDa subunit B antibody,
chromatin remodeling complex BAF60B subunit antibody,
mammalian chromatin remodeling complex BRG1-associated factor 60B antibody.