BAF53A Antibody

BAF53A is a 53kd subunit of the BAF (BRG1/brm-associated factor) complex, a SWI/SNF chromatin remodeling and histone acetyltransferase complex that functions in the regulation of gene transcription. In the BAF complex, BAF53A is important to the ATPase activity of SMARCA4/BRG1 and the association of the BAF complex with chromatin. BAF53A also appears to be important to the formation of higher-order chromatin structure and has been shown to associate with mitotic chromosomes. Recently, BAF53A has been found to interact with p53 and repress p53-mediated gene transcription in a BRG1-independent manner.

Alternative names for BAF53A Antibody include actin-like protein 6A antibody, 53kDa BRG1-associated factor A antibody, ArpNbeta antibody, ACTL6A antibody, BAF53 antibody, MGC5382 antibody.