The SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin (SMARC), also called BRG1-associated factors (BAFs), have been identified as components of the human SWI/SNF-like chromatin-remodeling protein complexes. SWI/SNF complexes possess ATPase and DNA helicase activity that promotes transcriptional activation of genes normally repressed by chromatin structure. ARID1A/BAF250 is a noncatalytic subunit that is a member of the ARID (AT-rich interactive domain-containing protein) family of DNA binding proteins. ARID1A/BAF250 has been shown to play a role in the tumor suppressor activity of the SWI/SNF complexes. ARID1A/BAF250 is required for differentiation-associated cell cycle arrest.
Alternative names for
BAF250/ARID1A Antibody include B120 antibody,
Osa homolog 1 antibody,
osa homolog 1 antibody,
AT-rich interactive domain-containing protein 1A antibody,
BRG1-associated factor 250 antibody,
BRG1-associated factor 250a antibody,
SWI-like protein antibody,
SWI/SNF complex protein p270 antibody,
SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1 antibody,
AT rich interactive domain 1ASWI-like) antibody,
brain protein 120 antibody,
OSA1 nuclear protein antibody,
chromatin remodeling factor p250 antibody,
ARID domain-containing protein 1A antibody.