Aurora B Antibody

Aurora B is the central enzymatic unit of the chromosomal passenger complex (CPC). In the CPC, Aurora B is associated with the passenger proteins inner centromeric protein (INCENP), survivin, and borealin. Aurora B is a serine-threonine protein kinase essential for chromosome segregation and cytokinesis. Specific roles for Aurora B have been demonstrated in cohesin dissociation from centromeres as well as condensin I binding to chromatin.F112. Substrates of Aurora B kinase activity include desmin, septin 1, INCENP, RAC GTPase activating protein 1, and centromeric protein A.

Alternative names for Aurora B Antibody include serine/threonine-protein kinase 12 antibody, Aurora-and lpl1-like midbody-associated protein 1 antibody, AIM-1 antibody, Aurora/IPL1-related kinase 2 antibody, Aurora-related kinase 2 antibody, STK-1 antibody, AURKB antibody, AIK2 antibody, AIM2 antibody, ARK2 antibody, STK12 antibody.