Ataxin-7 Antibody

Defects in ATXN7 are the cause of spinocerebellar ataxia type 7 (SCA7) also known as olivopontocerebellar atrophy III (OPCA III or OPCA3) or olivopontocerebellar atrophy with retinal degeneration. Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. Ataxin 7 acts as a component of the STAGA transcription coactivator-HAT complex. It mediates the interaction of STAGA complex with the CRX and is involved in CRX-dependent gene activation [taken from the Universal Protein Resource (UniProt)].
    Product Specifications
    Catalog # Size Price
    Ataxin-7 AntibodyReactivity: Human
    Applications: WB
    Immunogen: Between 842 and 892
    A302-638A100 µl (1 mg/ml) $339Add to Cart
    A302-638A-M100 µl (10 blots) $229Add to Cart
    A302-638A-T20 µl (2 blots) $50Add to Cart

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