Ataxin-1 Antibody

Defects in Ataxin-1 are the cause of spinocerebellar ataxia type 1 (SCA1), also known as olivopontocerebellar atrophy I (OPCA I or OPCA1). Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to cerebellum degeneration with variable involvement of the brainstem and spinal cord. SCA1 is caused by expansion of a CAG repeat in the coding region of the ataxin-1 gene. Longer expansions result in earlier onset and more severe clinical manifestations of the disease. Ataxin-1 binds RNA in vitro and may be involved in RNA metabolism [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P54253]
    Product Specifications
    Catalog # Size Price
    Ataxin-1 AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 350 and 400
    A302-291A100 µl (1 mg/ml) $339Add to Cart
    A302-291A-T10 µl (1 mg/ml) $50Add to Cart
    Ataxin-1 AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 766 and 816
    A302-292A100 µl (0.2 mg/ml) $339Add to Cart
    A302-292A-M100 µl (10 blots) $229Add to Cart
    A302-292A-T20 µl (2 blots) $50Add to Cart
    Applications: WB, IP
    Reactivity: Human
    Includes: 1 each of A302-291A and A302-292A
    A310-828A1 Pack $472Add to Cart

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