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By Research Area / Cell Cycle / Astrin/MAP126

Astrin/MAP126 Antibody

Astrin/MAP126 has been identified as a mitotic spindle-associated protein essential for centrosome integrity and the progression through mitosis. Astrin/MAP126 interacts with Ninein and Aurora-A at the centrosome. Ninein, but not Aurora-A, appears to be required for proper localization of Astrin/MAP126 to the centrosome during S and G2 phase. A pool of Astrin/MAP126 also localizes to the outer kinetochore where it plays an essential role in chromatid adhesion and chromosome congression and segregation. The localization of Astrin/MAP126 to the spindle pole and kinetochore has been shown to be dependent on its phosphorylation by glycogen synthase kinase 3beta (GSK3beta). Alternate names for Astrin/MAP126 include sperm-associated antigen 5, mitotic spindle-associated protein p126, deepest, and SPAG5.

Product / Catalog #	Specifications	Price
Astrin/MAP126 Antibody A301-511A	Applications: IP Reactivity: Human Quantity: 0.1 ml	$280.00 Data Sheet Add to Cart
Astrin/MAP126 Antibody A301-512A	Applications: WB, IP Reactivity: Human Quantity: 0.1 ml (20 - 100 blots)	$280.00 Data Sheet Add to Cart
Astrin/MAP126 Antibody AbVantage™ Pack A310-530A	Applications: WB, IP Reactivity: Human Quantity: 1 each of A301-511A and A301-512A	$390.00 Data Sheet Add to Cart
Astrin/MAP126 Blocking Peptide BP301-511	Applications: Blocks A301-511A Quantity: 50 mcg	$115.00 Data Sheet Add to Cart
Astrin/MAP126 Blocking Peptide BP301-512	Applications: Blocks A301-512A Quantity: 50 mcg	$115.00 Data Sheet Add to Cart

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