Astrin/MAP126 Antibody

Astrin/MAP126 has been identified as a mitotic spindle-associated protein essential for centrosome integrity and the progression through mitosis. Astrin/MAP126 interacts with Ninein and Aurora-A at the centrosome. Ninein, but not Aurora-A, appears to be required for proper localization of Astrin/MAP126 to the centrosome during S and G2 phase. A pool of Astrin/MAP126 also localizes to the outer kinetochore where it plays an essential role in chromatid adhesion and chromosome congression and segregation. The localization of Astrin/MAP126 to the spindle pole and kinetochore has been shown to be dependent on its phosphorylation by glycogen synthase kinase 3beta (GSK3beta).
    Product Specifications
    Catalog # Size Price
    Astrin/MAP126 AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 1 and 50
    A301-511A100 µl (1 mg/ml) $339Add to Cart
    A301-511A-T10 µl (1 mg/ml) $50Add to Cart
    Astrin/MAP126 AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 875 and 925
    A301-512A100 µl (0.2 mg/ml) $339Add to Cart
    A301-512A-M100 µl (10 blots) $229Add to Cart
    A301-512A-T20 µl (2 blots) $50Add to Cart

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