ADP-ribosylation factor GTPase activating protein 1 (ArfGAP1) is a GTPase activating protein that interacts with the GTPase ADP-ribosylation factor (Arf) in Golgi membranes and vesicles. ArfGAP1 promotes the hydrolysis of ARF1-bound GTP to promote fusion of golgi-derived vesicles with the target compartment. Although they are differentially regulated, ArfGAP1, ArfGAP2, and ArfGAP3 have been shown to play overlapping roles in COPI-mediated transport and in the maintenance of Golgi organization.
Alternative names for
ArfGAP1 Antibody include ARF1 GAP antibody,
ADP-ribosylation factor GTPase-activating protein 1 antibody,
ADP-ribosylation factor 1 GTPase-activating protein antibody,
ARF1-directed GTPase-activating protein antibody,
ADP-ribosylation factor GTPase activating protein 1 antibody.