Aly Antibody

Aly (ally of AML-1 and LEF-1) is a component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. Aly also functions as a chaperone and promotes the dimerization of transcription factors containing basic leucine zipper (bZIP) domains and thereby promotes transcriptional activation. Additionally, Aly plays a role in mRNA processing and export and may function as scaffold that mediates interactions between proteins and/or RNA. Aly is also part of the exon junction complex that remains associated with spliced mRNA and plays an important role in mRNA export and nonsense-mediated RNA decay. Aly directs mRNA derived from Herpes simplex virus intron-less genes to the NXF1-mediated export pathway [taken from the Universal Protein Resource (UniProt) Q886V81].
    Product Specifications
    Catalog # Size Price
    Aly AntibodyReactivity: Human
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 25 and 75
    A302-892A100 µl (1 mg/ml) $339Add to Cart
    A302-892A-M100 µl (10 blots) $229Add to Cart
    A302-892A-T20 µl (2 blots) $50Add to Cart
    Aly AntibodyReactivity: Human
    Applications: IP, IHC-P, IF
    Immunogen: Between 75 and 125
    A302-893A100 µl (1 mg/ml) $339Add to Cart
    A302-893A-T10 µl (1 mg/ml) $50Add to Cart
    Applications: WB, IP, IHC-P, IF
    Reactivity: Human
    Includes: 1 each of A302-892A and A302-893A
    A311-067A1 Pack $472Add to Cart

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