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By Research Area / Cell Cycle / ATR

ATR Antibody

ATR (ATM and Rad3 related) is closely related to ATM (Ataxia telangiectasia, mutated) and is a member of the phosphatidylinositol 3 kinase (PI-3) family that is an early sensor of DNA damage. ATR is a serine-threonine kinase that reacts to UV damage and interruptions in replication. ATR may be able to sense DNA damage through interaction with Rad17 and 1as well as components of nucleosome remodeling complexes. In response to DNA damage, ATR has been shown to phosphorylate a multitude of substrates which include BRCA1, p53, Chk2, Rad 17, and E2F transcription factor 1. ATR is also known as serine/threonine-protein kinase ATR, FRAP-related protein 1, FRP1, MEC1, SCKL, and SCKL1.

Product / Catalog #	Specifications	Price
ATR Antibody A300-137A	Applications: WB, IP Reactivity: Human, Mouse Quantity: 0.1 ml (150 - 300 blots)	$280.00 Data Sheet Add to Cart
ATR Antibody A300-138A	Applications: WB, IP Reactivity: Human, Mouse Quantity: 0.1 ml (150 - 300 blots)	$280.00 Data Sheet Add to Cart
ATR Antibody AbVantage™ Pack A310-035A	Applications: WB Reactivity: Human, Mouse Quantity: 1 each of A300-137A and A300-138A	$390.00 Data Sheet Add to Cart
ATR Antibody Agarose Immobilized S300-137	Applications: IP Reactivity: Human, Mouse Quantity: 0.1 mg antibody/200 mcl of gel	$295.00 Data Sheet Add to Cart
ATR Blocking Peptide BP300-137	Applications: Blocks A300-137A Quantity: 50 mcg	$115.00 Data Sheet Add to Cart
ATR Blocking Peptide BP300-138	Applications: Blocks A300-138A Quantity: 50 mcg	$115.00 Data Sheet Add to Cart

ATM and ATR Signaling
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