ATR Antibody

ATR (ATM and Rad3 related) is closely related to ATM (Ataxia telangiectasia, mutated) and is a member of the phosphatidylinositol 3 kinase (PI-3) family that is an early sensor of DNA damage. ATR is a serine-threonine kinase that reacts to UV damage and interruptions in replication. ATR may be able to sense DNA damage through interaction with Rad17 and 1as well as components of nucleosome remodeling complexes. In response to DNA damage, ATR has been shown to phosphorylate a multitude of substrates which include BRCA1, p53, Chk2, Rad 17, and E2F transcription factor 1.
    Product Specifications
    Catalog # Size Price
    ATR AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 400 and 450
    A300-137A100 µl (1 mg/ml) $339Add to Cart
    A300-137A-M100 µl (10 blots) $229Add to Cart
    A300-137A-T20 µl (2 blots) $50Add to Cart
    ATR AntibodyReactivity: Human
    Applications: WB, IP, PLA
    Immunogen: Between 1675 and 1725
    A300-138A100 µl (1 mg/ml) $339Add to Cart
    A300-138A-M100 µl (10 blots) $229Add to Cart
    A300-138A-T20 µl (2 blots) $50Add to Cart
    Reactivity: Human, Mouse
    Applications: IP
    Immunogen: Between 400 and 450
    S300-137100 µg $356Add to Cart
    Applications: WB, IP, PLA
    Reactivity: Human
    Includes: 1 each of A300-137A and A300-138A
    A310-035A1 Pack $472Add to Cart

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