ASXL2 Antibody

The gene that encodes Additional sex combs-like protein 2 (ASXL2) is a homolog of the drosophila additional sex combs (Asx) gene. Drosophila Asx is in a class of proteins known as ETP (enhancers of trithorax and polycomb). ETP proteins regulate polycomb-group (PcG) and trithorax-group (trxG) proteins which function to modify the methylation of histones and structure of chromatin. Mutations in ASXL1 are implicated in the development of myelodysplastic syndromes (MDS), a group of hematological diseases characterized by ineffective hematopoiesis and a predisposition to acute myeloid leukemia (AML).
    Product Specifications
    Catalog # Size Price
    ASXL2 AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 600 and 650
    A302-037A100 µl (1 mg/ml) $339Add to Cart
    A302-037A-M100 µl (10 blots) $229Add to Cart
    A302-037A-T20 µl (2 blots) $50Add to Cart

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