ASAP2 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 2) activates the small GTPases ARF1, ARF5 and ARF6. It regulates the formation of post-Golgi vesicles and modulates constitutive secretion. ASAP2 also modulates phagocytosis mediated by Fc gamma receptor and ARF6 as well as PXN recruitment to focal contacts and cell migration [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ O43150].
Alternative names for
ASAP2 Antibody include development and differentiation-enhancing factor 2 antibody, paxillin-associated protein with ARF GAP activity 3 antibody, PAG3 antibody, Pyk2 C-terminus-associated protein antibody, PAP antibody, DDEF2 antibody, KIAA0400 antibody.