ARMS Antibody

Ankyrin repeat-rich membrane-spanning protein (ARMS) is also known as Kinase D-interacting substrate of 220 kDa (KIDINS220). ARMS Promotes prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Arms may play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. ARMS may play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration. ARMS has also been shown to modulate stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9ULH0]
    Product Specifications
    Catalog # Size Price
    ARMS AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 1400 and 1450
    A303-002A100 µl (1 mg/ml) $339Add to Cart
    A303-002A-M100 µl (10 blots) $229Add to Cart
    A303-002A-T20 µl (2 blots) $50Add to Cart
    ARMS AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 1721 and 1771
    A303-003A100 µl (1 mg/ml) $339Add to Cart
    A303-003A-T10 µl (1 mg/ml) $50Add to Cart
    Applications: WB, IP
    Reactivity: Human
    Includes: 1 each of A303-002A and A303-003A
    A311-114A1 Pack $472Add to Cart

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