API5 (apoptosis inhibitor 5) is an antiapoptotic factor that may have a role in protein assembly. API5 negatively regulates ACIN1. By binding to ACIN1, API5 suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. API5 is also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.
Alternative names for
API5 Antibody include API-5 antibody, fibroblast growth factor 2-interacting factor antibody, FIF antibody, protein XAGL antibody, antiapoptosis clone 11 protein antibody, AAC-11 antibody, cell migration-inducing gene 8 protein antibody.