APC3 Antibody

CDC27 is a component of the APC/c (anaphase promoting complex/cyclosome) which is responsible for the ubiquitination and degradation of securin and cyclin B that prompts the onset of anaphase and exit from mitosis. The APC/c is composed of at least 11 subunits. Three subunits, CDC27 CDC16 and CDC23, contain a TPR (tetratricopeptide repeat) important for protein-protein interactions. CDC27 has been shown to interact with mitotic checkpoint proteins such as Mad2, p55CDC and BUBR1.

Alternative names for APC3 Antibody include cell division cycle 27 antibody, APC3 antibody, APC-3 antibody, anaphase-promoting complex antibody, protein 3 antibody, HNUC antibody, human nuc2 homolog antibody.