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APC
APC Antibody
Adenomatosis polyposis coli (APC) is a tumor suppressor gene found to be mutated in most colon cancers and is the cause of familial adenomatous polyposis (FAP), an autosomal dominant disease that results in a predisposition to malignant colon cancer. APC has been shown to be involved in cell differentiation, migration, proliferation and adhesion. One function of APC involves its role as a scaffolding protein that regulates the phosphorylation and degradation of beta-catenin, a transcriptional regulator in the WNT signaling pathway. Additionally, APC has been found to be important in the regulation of microtubule arrays and mitotic spindle formation. Alternate designations for APC include DP2.5, DP2, GS, FAP, FPC, and DP3.
Product / Catalog #
Specifications
Price
APC Antibody
A300-979A
Applications:
IP
Reactivity:
Human
Quantity:
0.1 ml
$280.00
Data Sheet
Add to Cart
APC Antibody
A300-980A
Applications:
IP
Reactivity:
Human
Quantity:
0.1 ml
$280.00
Data Sheet
Add to Cart
APC Antibody
A300-981A
Applications:
WB, IP
Reactivity:
Human
Quantity:
0.1 ml
$280.00
Data Sheet
Add to Cart
APC Antibody AbVantage™ Pack
A310-318A
Applications:
WB, IP
Reactivity:
Human
Quantity:
1 each of A300-979A, A300-980A and A300-981A
$585.00
Data Sheet
Add to Cart
APC IHC Antibody
IHC-00252
Applications:
IHC
Reactivity:
Human
Quantity:
0.1 ml (50 - 250 slides)
$360.00
Data Sheet
Add to Cart
APC Blocking Peptide
BP300-979
Applications:
Blocks A300-979A
Quantity:
50 mcg
$115.00
Data Sheet
Add to Cart
APC Blocking Peptide
BP300-980
Applications:
Blocks A300-980A
Quantity:
50 mcg
$115.00
Data Sheet
Add to Cart
APC Blocking Peptide
BP300-981
Applications:
Blocks A300-981A
Quantity:
50 mcg
$115.00
Data Sheet
Add to Cart
Product Focuses
ATM and ATR Signaling Proteins
Condensin Complex
GTPase Regulation
mTOR Signaling Pathway
NFKB
Nucleoporin
SWI/SNF
USP
WD-repeat
Xeroderma Pigmentosum
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Bethyl Laboratories, Inc.
P.O. Box 850
Montgomery, TX 77356
Phone: 1-800-338-9579
Fax: 1-866-597-6105