AKAP95/AKAP8 Antibody

AKAP8/AKAP95 has been characterized as a 95 kDa protein kinase A (PKA)-anchoring protein and regulatory subunit of PKA that functions to recruit the condensin complex for chromosome condensation during mitosis. A role in DNA replication has also been demonstrated through its interaction with the pre-replication complex component, MCM2 (mini-chromosome maintenance 2). Inhibition of AKAP8/AKAP95 association with MCM2 inhibits replication initiation and elongation in vitro. AKAP8/AKAP95 has also been shown to be involved in apoptosis. KAP8/AKAP95 associates with caspase 3 and serves as a carrier to transport caspase 3 from the cytoplasm to the nucleus to induce morphological changes in the nucleus.
    Product Specifications
    Catalog # Size Price
    AKAP8/AKAP95 AntibodyReactivity: Human
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 575 and 625
    A301-061A100 µl (0.2 mg/ml) $339Add to Cart
    A301-061A-M100 µl (10 blots) $229Add to Cart
    A301-061A-T20 µl (2 blots) $50Add to Cart
    AKAP8/AKAP95 AntibodyReactivity: Human, Mouse
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 642 and C-term
    A301-062A100 µl (0.2 mg/ml) $339Add to Cart
    A301-062A-M100 µl (10 blots) $229Add to Cart
    A301-062A-T20 µl (2 blots) $50Add to Cart

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