AKAP9/CG-NAP is a member of the A-kinase anchoring protein family that functions as a molecular scaffold for the subcellular compartmentalization of A- kinase signaling molecules. AKAP9/CG-NAP has been found to be critical to repolarization in the human heart. Defects in AKAP9/CG-NAP result in long QT syndrome type 11, a heart disorder characterized by ventricular arrhythmia and prolonged QT intervals. AKAP9/CG-NAP has been shown to form a multiprotein complex with the I(Ks) potassium channel subunit and play an essential role in its phosphorylation by PKA. AKAP9/CG-NAP is also important to centrosome and microtubule cytoskeletal organization.
Alternative names for
AKAP9/CG-NAP Antibody include A-kinase anchor protein 9 antibody, protein kinase A-anchoring protein 9 antibody, PRKA9 antibody, A-kinase anchor protein 450 kDa antibody, AKAP450 antibody, AKAP350 antibody, AKAP 120-like protein antibody, protein hyperion antibody, protein yotiao antibody, centrosome- and golgi-localized PKN-associated protein antibody, KIAA0803 antibody.