AKAP8/AKAP95 Antibody

AKAP8/AKAP95 has been characterized as a 95 kDa protein kinase A (PKA)-anchoring protein and regulatory subunit of PKA that functions to recruit the condensin complex for chromosome condensation during mitosis. A role in DNA replication has also been demonstrated through its interaction with the pre-replication complex component, MCM2 (mini-chromosome maintenance 2). Inhibition of AKAP8/AKAP95 association with MCM2 inhibits replication initiation and elongation in vitro. AKAP8/AKAP95 has also been shown to be involved in apoptosis. KAP8/AKAP95 associates with caspase 3 and serves as a carrier to transport caspase 3 from the cytoplasm to the nucleus to induce morphological changes in the nucleus.
    Product/Catalog #SpecificationsPrice
    AKAP8/AKAP95 Antibody
    A301-061A
    Reactivity: Human
    Applications: WB, IP, IHC-P, IF
    $314.00
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    AKAP8/AKAP95 Antibody
    A301-062A
    Reactivity: Human, Mouse
    Applications: WB, IP, IHC-P, IF
    $314.00
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    Data Sheet
    Add to Cart
    AKAP8/AKAP95 Antibody AbVantage™ Pack
    A310-346A
    Applications: WB, IP, IHC-P, IF
    Reactivity: Human
    Quantity: 1 each of A301-061A and A301-062A
    $437.00
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    AKAP8/AKAP95 IHC Antibody
    IHC-00217
    Applications: IHC-P, IF
    Reactivity: Human, Mouse
    Quantity: 0.1 ml (50 - 250 slides)
    $360.00
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