A20 Antibody

Zinc-finger protein A20 was identified as a transcript that was rapidly induced by tumor-necrosis factor alpha (TNF-alpha). A20 is an essential component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. Upon TNF stimulation, A20 deubiquitinates 'Lys-63'-polyubiquitin chains on RIPK1 and catalyzes the formation of 'Lys-48'-polyubiquitin chains [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P21580].
    Product Specifications
    Catalog # Size Price
    A20 AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 525 and 575
    A302-633A100 µl (1 mg/ml) $339Add to Cart
    A302-633A-M100 µl (10 blots) $229Add to Cart
    A302-633A-T20 µl (2 blots) $50Add to Cart

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