14-3-3 Sigma Antibody

14-3-3 sigma was identified as an epithelial cell marker. It is part of the 14-3-3 family of proteins in which seven isoforms have been identified: beta, zeta, gamma, eta, epsilon, tau, and sigma. 14-3-3 proteins function as adaptors that bind with a number of partners to mediate various signaling pathways. 14-3-3 sigma is also called stratifin or HME1 and appears to function as a tumor suppressor whose expression can be downregulated via methylation. Loss of 14-3-3 sigma expression results in a defective G2/M phase checkpoint and appears to contribute to both epithelial and non-epithelial tumorigenesis.
    Product Specifications
    Catalog # Size Price
    14-3-3 Sigma AntibodyReactivity: Human
    Applications: WB, IP, IHC-P, IF, PLA
    Immunogen: Between 198 and 248
    A301-648A100 µl (1 mg/ml) $339Add to Cart
    A301-648A-M100 µl (10 blots) $229Add to Cart
    A301-648A-T20 µl (2 blots) $50Add to Cart

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