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14-3-3 Sigma
14-3-3 Sigma Antibody
14-3-3 sigma was identified as an epithelial cell marker. It is part of the 14-3-3 family of proteins in which seven isoforms have been identified: beta, zeta, gamma, eta, epsilon, tau, and sigma. 14-3-3 proteins function as adaptors that bind with a number of partners to mediate various signaling pathways. 14-3-3 sigma is also called stratifin or HME1 and appears to function as a tumor suppressor whose expression can be downregulated via methylation. Loss of 14-3-3 sigma expression results in a defective G2/M phase checkpoint and appears to contribute to both epithelial and non-epithelial tumorigenesis. Alternate names for 14-3-3 sigma include epithelial marker protein 1, SFN and YWHAS.
Product / Catalog #
Specifications
Price
14-3-3 Sigma Antibody
A301-648A
Applications:
WB, IP
Reactivity:
Human
Quantity:
0.1 ml (20 - 100 blots)
$280.00
Data Sheet
Add to Cart
14-3-3 Sigma IHC Antibody
IHC-00346
Applications:
IHC, IHC-IF
Reactivity:
Human
Quantity:
0.1 ml (50 - 250 slides)
$360.00
Data Sheet
Add to Cart
14-3-3 Sigma Blocking Peptide
BP301-648
Applications:
Blocks A301-648A
Quantity:
50 mcg
$115.00
Data Sheet
Add to Cart
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