ZBTB7B Antibody

ZBTB7B is a transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. ZBTB7B is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is also a transcriptional repressor of the collagen COL1A1 and COL1A2 genes and may also function as a repressor of fibronectin and possibly other extracellular matrix genes [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ O15156].
ZBTB7B
zinc finger and BTB domain containing 7B
Zinc finger and BTB domain-containing protein 7B
:  CKROX c-Krox hcKrox krueppel-related zinc finger protein cKrox T-helper-inducing POZ/Krueppel-like factor THPOK ZBTB15 ZFP67 ZFP-67 zinc finger and BTB domain containing 15 Zinc finger and BTB domain-containing protein 15 zinc finger protein 67 homolog zinc finger protein 67 homolog (mouse) zinc finger protein 857B zinc finger protein Th-POK ZNF857B More... Less...
Product
Specifications
Ordering Information
Human
WB, IP
Between 200 and 250
100
$339
$229
$99