WDR77/MEP50 Antibody

WDR77/MEP50 is a component of the methylosome, a large protein arginine methyltransferase complex that modifies specific arginines to dimethylarginines in splicesomal Sm proteins. WDR77/MEP50 associates with the methyltransferase JBP1 (PRMT5) and is important for methylosome activity. WDR77/MEP50 has also been shown to associate with the polycomb group protein, SUZ12, and histone H2A. In this context, WDR77/MEP50 is proposed to function as an adaptor between PRMT5 and its substrate H2A to regulate transcription.
WDR77
WD repeat domain 77
Methylosome protein 50
:  androgen receptor cofactor p44 HKMT1069 MEP50 MEP-50 methylosome protein 50 Nbla10071 p44 p44/Mep50 testis tissue sperm-binding protein Li 44a WD repeat-containing protein 77
Product
Specifications
Ordering Information
Human
IP, IHC-P
Between 1 and 50
$339
$99
Human
WB, IP, IHC-P
Between 292 and 342
$339
$229
$99
Human
Includes: 1 each of A301-561A and A301-562A
$472
Includes: 1 each of A301-561A and A301-562A
Human, Mouse
IHC-P, IF
Between 292 and 342
$360
$99