VRK1 Antibody

Vaccinia-related kinase 1 is a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases.VRK1 is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This protein, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN [taken from NCBI Entrez Gene (Gene ID: 7443)].
VRK1
vaccinia related kinase 1
Serine/threonine-protein kinase VRK1
:  PCH1 PCH1A vaccinia virus B1R-related kinase 1 vaccinia-related kinase 1
Product
Specifications
Ordering Information
Human
IP
between 1 and 50
100
$339
$99
Human
WB, IP
between 346 and 396
100
$339
$229
$99
Human
100
Includes: 1 each of A305-268A and A305-269A
$472
Includes: 1 each of A305-268A and A305-269A