TDG Antibody

Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine [taken from NCBI Entrez Gene (Gene ID: 6996)].
TDG
thymine DNA glycosylase
G/T mismatch-specific thymine DNA glycosylase
:  G/T mismatch-specific thymine DNA glycosylase hTDG thymine-DNA glycosylase
Product
Specifications
Ordering Information
Human
WB, IP, IHC-P
Between 360 to 410
$339
$229
$99