STIM2 Antibody

STIM2 (stromal interaction molecule 2) plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Stim2 functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx. It regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, STIM2 translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+) (CRAC) channels ORAI1, ORAI2 and ORAI. STIM2 may inhibit STIM1-mediated Ca(2+) influx  [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9P246].
STIM2
stromal interaction molecule 2
Stromal interaction molecule 2
Product
Specifications
Ordering Information
Human, Mouse
WB, IP
Between 600 to 650
$339
$229
$99
Human, Mouse
WB, IP
Between 650 to 700
$339
$229
$99
Human, Mouse
Includes: 1 each of A304-429A and A304-430A
$472
Includes: 1 each of A304-429A and A304-430A