Spartan (SPRTN) may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein (p97) to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation [taken from NCBI Entrez Gene (Gene ID: 83932)].
chromosome 1 open reading frame 124•
DNA damage protein targeting VCP•
DNA damage-targeting VCP (p97) adaptor•
Protein with SprT-like domain at the N terminus•
SprT-like domain at the N terminus•
zinc finger RAD18 domain-containing protein•More...Less...