SPG20 Antibody

Spastic paraplegia 20 protein (SPG20) is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Mutations associated with the SPG20 gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome) [taken from NCBI Entrez Gene (Gene ID: 23111)].
SPG20
spastic paraplegia 20 (Troyer syndrome)
Spartin
:  KIAA0610 spartin Spastic paraplegia 20 protein TAHCCP1 trans-activated by hepatitis C virus core protein 1
Product
Specifications
Ordering Information
Human
WB, IP
between 350 and 400
$339
$229
$99
Human
IP
between 500 and 550
$339
$99
Human
Includes: 1 each of A305-375A and A305-376A
$472
Includes: 1 each of A305-375A and A305-376A