The transcription of RNA is a multi-stage process catalyzed by the multisubunit complex RNA Polymerase II (RNA Pol II) that involves the polymerization of nucleoside monophosphates into a ribonucleotide transcript from a DNA template. The RNA Pol II core complex is composed of 12 subunits (Rpb1-Rbp12). Rpb2 is proposed to form the enzyme’s catalytic center and function to maintain contact in the active site of the enzyme between the DNA template and the newly synthesized RNA.
DNA-directed RNA polymerase II 140 kDa polypeptide•
DNA-directed RNA polymerase II subunit B•
polymerase (RNA) II (DNA directed) polypeptide B (140kD)•
polymerase (RNA) II (DNA directed) polypeptide B, 140kDa•
RNA polymerase II second largest subunit•
RNA polymerase II subunit 2•
RNA polymerase II subunit B2•