Retinoblastoma-binding protein 6 (RBBP6) is an E3 ubiquitin-protein ligase which promotes ubiquitination of YBX1, leading to its degradation by the proteasome (PubMed:18851979). RBBP3 may play a role as a scaffold protein to promote the assembly of the p53/TP53-MDM2 complex, resulting in increase of MDM2-mediated ubiquitination and degradation of p53/TP53. It may function as negative regulator of p53/TP53, leading to both apoptosis and cell growth (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q7Z6E9].
p53-associated cellular protein of testis•
proliferation potential-related protein•
RB-binding Q-protein 1•
retinoblastoma binding protein 6•
retinoblastoma-binding protein 6•
retinoblastoma-binding Q protein 1•