NUMA Antibody

The nuclear mitotic apparatus protein (NuMA) is a critical component of the mitotic spindle that is responsible for organizing minus-ends of microtubules at spindle poles. NUMA is regulated by phosphorylation and associates with dynein and dynactin in its phosphorylated form. Dephosphorylation of NUMA in anaphase results in the release from dynein and dynactin to allow spindle disassembly. NUMA, in association with dynein and dynactin, also interacts with 4.1R in a complex of spindle pole organizing proteins. Other NUMA interacting proteins include GAS41, tankyrase, and Rae1. These interactions indicate a broader role for NUMA function in the nucleus.
NUMA1
nuclear mitotic apparatus protein 1
Nuclear mitotic apparatus protein 1
:  centrophilin stabilizes mitotic spindle in mitotic cells NMP-22 nuclear matrix protein-22 NUMA NuMA protein SP-H antigen structural nuclear protein
Product
Specifications
Ordering Information
Human
WB, IP, IHC-P, IF
Between 900 and 950
100
$339
$229
$99
Human
WB, IP, IHC-P
Between 2065 and 2115
100
$339
$229
$99
Human
100
Includes: 1 each of A301-509A and A301-510A
$472
Includes: 1 each of A301-509A and A301-510A
Human
IHC-P, IF
Between 900 and 950
100
$360
$99