Fibrillarin Antibody

Fibrillarin is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. Fibrillarin contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin [taken from NCBI Entrez Gene (Gene ID: 2091)].
FBL
fibrillarin
rRNA 2'-O-methyltransferase fibrillarin
:  34 kDa nucleolar scleroderma antigen 34-kD nucleolar scleroderma antigen FIB FLRN histone-glutamine methyltransferase RNA, U3 small nucleolar interacting protein 1 RNU3IP1
Product
Specifications
Ordering Information
Human, Mouse
WB
Between 1 and 50
$339
$229
$99
Human, Mouse
WB, IP
Between 271 and 321
$339
$229
$99
Human, Mouse
Includes: 1 each of A303-890A and A303-891A
$472
Includes: 1 each of A303-890A and A303-891A