DHX36 Antibody

DHX36 is a member of the DEAH box family of proteins that possesses several conserved motifs which include the highly conserved DEAH (Asp-Glu-Ala-His) amino acid sequence motif. The major activity of DEAH box proteins is to function as ATP-dependent RNA helicases. RNA helicases play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DHX36 expression is highest in testis and plays a role in 3’-5’ degradation of AU-rich RNAs. Interestingly, DHX36 has also been observed to function as a G4-DNA resolvase. In this capacity DHX36 catalyzes the resolution of highly stable G4- DNA structures that form in guanine-rich regions of single-stranded DNA.
DEAH-box helicase 36
ATP-dependent RNA helicase DHX36
:  DDX36 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 DEAH box protein 36 G4 resolvase-1 G4R1 G4-resolvase 1 KIAA1488 MLEL1 MLE-like protein 1 probable ATP-dependent RNA helicase DHX36 RHAU RNA helicase associated with AU-rich element ARE More... Less...
Ordering Information
Human, Mouse
Between 950 and C-term