DHX16 Antibody

DHX16 is a member of the DEAH-box family of proteins that possesses several conserved motifs which include the highly conserved DEAH (Asp-Glu-Ala-His) amino acid sequence motif. The major activity of DEAH-box proteins is to function as ATP-dependent RNA helicases. RNA helicases play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DH16 was originally identified as DBP2 and discovered to be a functional homolog of the yeast RNA helicase and ATPase, Cdc28/Prp68. DHX16 appears to play a key role in nonsense-mediated mRNA decay (NMD) as well as rRNA processing.
DEAH-box helicase 16
Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16
:  ATP-dependent RNA helicase #3 DBP2 DDX16 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 16 DEAD/H box 16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 DEAH-box protein 16 PRO2014 Prp2 PRP8 PRPF2 RNA helicase
Ordering Information
Between 991 and 1041