PYGL Antibody

Glycogen phosphorylase, liver form, (PYGL) encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores. This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15. Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls. Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively. The liver isozyme serves the glycemic demands of the body in general while the brain and muscle isozymes supply just those tissues [taken from NCBI Entrez Gene (Gene ID: 5836)].
PYGL
phosphorylase, glycogen, liver
Glycogen phosphorylase, liver form
:  glycogen phosphorylase, liver form glycogen storage disease type VI GSD6 Hers disease phosphorylase, glycogen; liver
Product
Specifications
Ordering Information
Human, Mouse
WB, IP
Between 797 to 847
$339
$229
$99