MCSP Antibody

Melanoma chondroitin sulfate proteoglycan (MCSP) is a cell-surface antigen expressed early in melanoma progression. It has been found to be involved in the spreading, invasion, and migration of human melanoma. MCSP influences melanoma behavior via the activation of the Cdc42 GTPase and phosphorylation of p130Cas. MCSP also activates signaling cascades involving FAK and ERK1/ERK2. In addition to its expression in melanoma cells, MCSP is also found in breast carcinomas, gliomas, neuroblastomas, and acute leukemias. MCSP is being considered as a target antigen for cancer immunotherapy.
CSPG4
chondroitin sulfate proteoglycan 4
Chondroitin sulfate proteoglycan 4
:  chondroitin sulfate proteoglycan 4 (melanoma-associated) chondroitin sulfate proteoglycan NG2 HMW-MAA MCSP MCSPG melanoma chondroitin sulfate proteoglycan melanoma-associated chondroitin sulfate proteoglycan MEL-CSPG MSK16 NG2
Product
Specifications
Ordering Information
Human
WB, IP
Between 575 and 625
$339
$229
$99
Human
WB, IP
Between 2272 and 2322
$339
$229
$99
Human
Includes: 1 each of A302-121A and A302-122A
$472
Includes: 1 each of A302-121A and A302-122A