DDX3 Antibody

DDX3 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DDX3 exhibits a variety of functions. DDX3 is a candidate tumor suppressor that suppresses tumor growth and transcriptionally activates the p21 promoter. DDX3 has been shown to play a role in translation as an eIF4E inhibitory protein that regulates translation initiation. These findings, as well as the observation that DDX3 is regulated by hepatitis C virus and is down-regulated in hepatocellular carcinoma, suggest an important role for DDX3 in growth-regulatory functions.
DDX3X
DEAD-box helicase 3, X-linked
ATP-dependent RNA helicase DDX3X
:  CAP-Rf DBX DDX14 DDX3 DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked DEAD box protein 3, X-chromosomal DEAD box, X isoform DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 DEAD/H box-3 helicase-like protein 2 HLP2 MRX102 More... Less...
Product
Specifications
Ordering Information
Human, Mouse
WB, IP, IHC-P
Between 1 and 50
$339
$229
$99
Human
WB, IP
Between 550 and 600
$339
$229
$99
Human
WB, IP
Between 600 and C-term
$339
$229
$99
Human, Mouse
Includes: 1 each of A300-474A, A300-475A and A300-476A
$707
Includes: 1 each of A300-474A, A300-475A and A300-476A
Human, Mouse
IHC-P
Between 1 and 50
$360
$99