DDX17 Antibody

DDX17 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. Some members of the DEAD box proteins also exhibit functions involved in transcriptional regulation. In addition to a role involved in RNA splicing, DDX17 has been observed to interact with and act as a transcriptional coactivator for estrogen receptor alpha (ERalpha). DDX17 is closely related to and forms heterodimers with DDX5.
DEAD-box helicase 17
Probable ATP-dependent RNA helicase DDX17
:  DEAD (Asp-Glu-Ala-Asp) box helicase 17 DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 DEAD box protein 17 DEAD box protein p72 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 17 (72kD) P72 RH70 RNA-dependent helicase p72
Ordering Information
Human, Mouse, Rat
Between 550 and C-term
Between 550 and C-term