Cyclin T1 Antibody

Cyclin T1 is a regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to productive elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNA Pol II). In case of HIV or SIV infections, Cyclin T1 binds to the transactivation domain of the viral nuclear transcriptional activator, Tat, thereby increasing Tat's affinity for the transactivating response RNA element (TAR RNA) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O60563].
CCNT1
cyclin T1
Cyclin-T1
:  CCNT CDK9-associated C-type protein cyclin C-related protein Cyclin-T CYCT1 HIVE1 human immunodeficiency virus type 1 (HIV-1) expression (elevated) 1
Product
Specifications
Ordering Information
Human
WB, IP, IHC-P
Between 250 and 300
100
$339
$229
$99
Human
WB, IP, IHC-P
Between 325 and 375
100
$339
$229
$99
Human
WB, IP, IHC-P
Between 425 and 475
100
$339
$229
$99
Human
WB, IP, IHC-P, PLA
Between 625 and 675
100
$339
$229
$99
Human
100
Includes: 1 each of A303-496A, A303-497A, A303-498A and A303-499A
$937
Includes: 1 each of A303-496A, A303-497A, A303-498A and A303-499A