Rb1 Antibody

Retinoblastoma 1 (Rb1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. Rb1 has also been found to stabilize constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma [taken from NCBI Entrez Gene (GeneID: 5925)].
RB transcriptional corepressor 1
Retinoblastoma-associated protein
:  exon 17 tumor GOS561 substitution mutation causes premature stop GOS563 exon 17 substitution mutation causes premature stop OSRC osteosarcoma p105-Rb pp110 PPP1R130 pRb prepro-retinoblastoma-associated protein protein phosphatase 1, regulatory subunit 130 RB retinoblastoma 1 retinoblastoma suspectibility protein More... Less...
Ordering Information
Between 550 and 600