FBP17 Antibody

FBP17 may act as a link between RND2 signaling and regulation of the actin cytoskeleton. FBP17 is required for the coordination of membrane tubulation and reorganization of the actin cytoskeleton during endocytosis. FBP17 binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. It also enhances actin polymerization via the recruitment of WASL/N-WASP, which in turn activates the Arp2/3 complex. FBP17 may be required for the lysosomal retention of FASLG/FASL [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q96RU3].
FNBP1
formin binding protein 1
Formin-binding protein 1
:  FBP17 formin-binding protein 17 hFBP17 KIAA0554
Product
Specifications
Ordering Information
Human
WB, IP
Between 350 and 400
$339
$229
$99
Human
WB, IP
Between 567 and 617
$339
$229
$99
Human
Includes: 1 each of A302-790A and A302-791A
$472
Includes: 1 each of A302-790A and A302-791A