ATR Antibody

ATR (ATM and Rad3 related) is closely related to ATM (Ataxia telangiectasia, mutated) and is a member of the phosphatidylinositol 3 kinase (PI-3) family that is an early sensor of DNA damage. ATR is a serine-threonine kinase that reacts to UV damage and interruptions in replication. ATR may be able to sense DNA damage through interaction with Rad17 and 1as well as components of nucleosome remodeling complexes. In response to DNA damage, ATR has been shown to phosphorylate a multitude of substrates which include BRCA1, p53, Chk2, Rad 17, and E2F transcription factor 1.
ATR
ATR serine/threonine kinase
Serine/threonine-protein kinase ATR
:  ataxia telangiectasia and Rad3 related ataxia telangiectasia and Rad3-related protein FCTCS FRAP-related protein 1 FRAP-related protein-1 FRP1 MEC1 MEC1, mitosis entry checkpoint 1, homolog MEC1, mitosis entry checkpoint 1, homolog (S. cerevisiae) SCKL SCKL1
Product
Specifications
Ordering Information
Human
WB, IP
Between 400 and 450
100
$339
$229
$99
Human
WB, IP, PLA
Between 1675 and 1725
100
$339
$229
$99
Human, Mouse
IP
Between 400 and 450
100
$356
Human
100
Includes: 1 each of A300-137A and A300-138A
$472
Includes: 1 each of A300-137A and A300-138A