ARS2 Antibody

Arsenate resistance protein 2 (ARS2) acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. ARS2 contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. ARS2 does not directly confer arsenite resistance but rather modulates arsenic sensitivity. Independently of its activity on miRNAs, it is necessary and sufficient to promote neural stem cell self-renewa and does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BXP5].
SRRT
serrate, RNA effector molecule
Serrate RNA effector molecule homolog
:  ARS2 arsenate resistance protein 2 arsenate resistance protein ARS2 arsenite resistance protein arsenite-resistance protein 2 Asr2 serrate serrate RNA effector molecule homolog (Arabidopsis)
Product
Specifications
Ordering Information
Human, Mouse
WB, IP
Between 1 to 50
$339
$229
$99
Human, Mouse
WB, IP, IHC-P
Between 826 to 876
$339
$229
$99
Human, Mouse
Includes: 1 each of A304-550A and A304-551A
$472
Includes: 1 each of A304-550A and A304-551A